Epidemiology of pediatric uveitis and associated systemic diseases
نویسندگان
چکیده
Abstract Background The early detection of uveitis associated with systemic inflammatory disease in children is important for proper treatment and prognosis. However, the diagnosis may be delayed because difficulties childhood examinations minor symptoms. objective our study was to identify pattern investigate frequency clinical features rheumatic diseases pediatric patients uveitis. Methods This retrospective observational reviewed medical records (age ≤ 18 years) at a Korean tertiary hospital between January 2005 December 2018. Data collected included age onset uveitis, sex, anatomic location ocular inflammation, comorbid (including disease), complications, relevant laboratory data, treatment. Fisher’s exact test used compare categorical variables Mann–Whitney U continuous variables. A p -value < 0.05 considered statistically significant. Results total 155 were this study. median 13.0 years (interquartile range, 9.5–16.0 years). male-to-female ratio 1.09. process unilateral 51.6% children. Anterior panuveitis, intermediate posterior represented 51.6, 26.5, 6.5, 1.9% cases, respectively. Idiopathic (65.2%) most frequent type Systemic associations responsible 28.4% among which juvenile idiopathic arthritis (JIA) cause (14.8%). Human leukocyte antigen (HLA)-B27 antinuclear antibody (ANA) positive rates significantly higher JIA than those ( = 0.006 0.007, respectively). Conclusions Approximately one-third Korea have disease, accounts majority cases. HLA-B27 ANA can serve as risk factors JIA-associated
منابع مشابه
Pediatric Uveitis
Uveitis is less common in children than in adults, and its diagnosis and management can be particularly challenging. Young children are often asymptomatic either because of inability to express complaints or because of the truly asymptomatic nature of their disease. Even in advanced cases, parents may not be aware of severe visual impairment until the development of externally visible changes s...
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A prospective study was conducted of 865 patients with uveitis to determine the frequency of associated systemic diseases and to assess the value of limited laboratory screening of these patients. All patients underwent a standard diagnostic protocol followed--when indicated--by special tests and procedures performed in order of likelihood ('tailored approach'). For 628 patients (73%) a specifi...
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Pediatric uveitis is a topic of special interest not only because of the unique diagnostic and therapeutic challenges but also because of the lifetime burden of vision loss if the problem is not adequately treated, as well as the economic and psychological toll on the family. Often, uveitis in children is discovered as part of a routine eye exam; this silent, insidious inflammation can be diffi...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2021
ISSN: ['1546-0096']
DOI: https://doi.org/10.1186/s12969-021-00516-2